Similac Pro Sensitive Vs All Similac Formulas: Full Comparison

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Similac Pro Sensitive is a lactose-reduced formula, made from milk protein isolate and 1% lactose, the other carbohydrate sources are corn syrup and sugar, designed for babies with gas and fussiness due to lactose sensitivity. Moreover, it has an HMO’s prebiotic (2′-FL) to help the immune system and digestive health.

According to moms’ reviews, it shows good results for fussiness and reflux, also it has good taste. However, it’s too foamy and may cause gas for some babies.

In this article, we will dive into a full comparison between Similac Pro Sensitive and all Similac Formulas to choose the best alternative to this one.

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Similac Sensitive vs Similac Pro Sensitive:

Similac Sensitive vs Similac Pro Sensitive

Similac Sensitive and Pro Sensitive are similar (lactose-reduced formulas), they have the same protein, carbohydrate, and fat source, also the same nutrient value.

The only difference between them is in the prebiotics; Similac Pro Sensitive has two prebiotics (2′-FL HMO and FOS) whereas Similac Sensitive has only one prebiotic which is Short-chain Fructooligosaccharides (FOS).

Related: Best 7 Generic Brands of Similac Sensitive and Pro Sensitive

2′-FL (Fucosyl Lactose) is a prebiotic that resembles chemically more than other prebiotics to that found in breast milk (Human Milk Oligosaccharides, or HMO’s).

« HMOs are special prebiotics found naturally in a mother’s breast milk. They are the most abundant solid ingredient in breast milk after fat and carbohydrates. In breastfed babies, HMOs are scientifically shown to positively affect the microbiome. » says nutritionnews.Abbott

Prebiotics are food for healthy bacteria (probiotics), they help them grow and do their job very well; which is helping the immune system develop properly and easing digestion.

Nutrition Comparison:

Price Comparison:

Similac SensitiveSimilac Pro Sensitive
12.5 oz
17.46 $
1.40/oz

34.9 oz
37.92 $
1.09 /oz


32 fl oz
7.82$
24.4 ¢/fl oz
29.8 oz
36.96 $
1.24 /oz

32 fl oz
8.12$
25.4 ¢/fl oz
4.5 of 5.0
1482 reviews
4.3 of 5.0
895 reviews

Buy 12.5 oz HERE

Buy 34.9 oz HERE

Buy Ready-to-feed

Buy 29.8 oz HERE

Buy Ready-to-feed

Mom’s Reviews Comparison:

Can you switch between Similac Sensitive and Pro Sensitive?

Yes, you can feed your baby Similac Sensitive and Pro Sensitive interchangeably because they are of the same type (lactose-reduced formulas) and have the same ingredients and nutrient value. The absence of the 2′-FL HMO prebiotic doesn’t have a negative impact on your baby’s health, babies are doing great!!

Similac Pro Sensitive vs Similac Total Comfort vs Similac Pro Total Comfort:

Similac Pro Sensitive vs Similac Total Comfort vs Similac Pro Total Comfort

The difference between Similac Pro Sensitive, Similac Total Comfort, and Pro Total Comfort is that these late have a partially hydrolyzed 100% whey protein and use corn maltodextrin among carbs sources whereas Pro Sensitive has an intact protein (milk protein isolate) with 18% of whey and 82% of casein. In terms of carbohydrate sources, it contains corn syrup instead of corn maltodextrin.

Related: Best 6 Generic Brands of Similac Total Comfort and Pro Total Comfort

Furthermore, Similac Total Comfort has one prebiotic (FOS) while Pro Sensitive and Pro total Comfort have two prebiotics (2′-FL HMO and FOS) to help good bacteria (probiotics) grow and do their job.

The difference between whey and casein is that the latter takes time to be digested which makes it good at night whereas whey is digested quickly by the body.

Other than that, they are similar; lactose-reduced by 99%, and have the same ingredients and nutrient value; they are good alternatives to each other.

A partially hydrolyzed formula is a formula that breakdown the protein a little bit in size to be gentle on babies’ tummies and to not elicit allergic responses by the immune system of babies who have intact cow’s milk protein allergy.

Image source: Nestle Health Science

Mom’s Reviews Comparison:

Nutrition Comparison:

Price Comparison:

Similac
Pro Sensitive
29.8 oz
36.96 $
1.24 /oz
Buy 29.8 oz HERE

32 fl oz
8.12$
25.4 ¢/fl oz

Buy Ready-to-feed
Similac
Total Comfort
12.6 oz
17.99 $
1.43/oz
Buy 12.6 oz HERE
Similac Pro
Total Comfort
22.5 oz
28.98 $
1.29 /oz
Buy 22.5 oz HERE

29.8 oz
36.96 $
1.24 /oz
Buy 29.8 oz HERE

32-fl-oz
11.30$
35.3 ¢/fl oz
Buy Ready-to-feed

Can you switch between Similac Pro Sensitive, Similac Total Comfort, and Pro Total Comfort?

Yes, you can switch between Similac Pro Sensitive, Similac Total Comfort, and Pro Total Comfort as you want in case your baby has a sensitivity to lactose. However, make sure he hasn’t an intact cow’s milk protein allergy, in that case, the only switching you can make is from Pro Sensitive to Similac Total Comfort or Pro Total Comfort because they have a partially hydrolyzed protein.

Similac Pro Sensitive vs Similac 360 Total Care Sensitive:

Similac Pro Sensitive vs Similac 360 Total Care Sensitive

Similac Pro Sensitive and Similac 360 Total Care Sensitive are similar; they are lactose-reduced formulas and are using the same protein source (milk protein isolate), also they have exactly the same nutrient value.

However, they slightly differ in lactose percentage and prebiotics; Similac Pro sensitive has 1% of lactose and 2 prebiotics whereas 360 Total Care Sensitive has 2% of lactose and has 5 HMO’s prebiotics (2′-FL HMO, Lacto-N-Tetraose, 3-Fucosyllactose, 6′-Sialyllactose, 3′-Sialyllactose) which will help the immune system, brain development, and digestive health.

Ingredients Comparison:

Nutrition Comparison:

In terms of nutrition, 360 Total Care Sensitive and Similac Sensitive have the same nutrition value.

Mom’s Reviews Comparison:

Price Comparison:

In terms of price, Similac Pro Sensitive is way cheaper (1.24$/oz) than 360 Total Care Sensitive (1.49$/oz), but the latter shows better results and isn’t a part of the recall.

Similac
Pro Sensitive
Similac 360
Total Care Sensitive
29.8 oz
36.96 $
1.24 /oz


32 fl oz
8.12$
25.4 ¢/fl oz
30.2 oz
44.88 $
1.49 /oz
4.3 of 5.0
895 reviews
4.8 of 5.0
604 reviews
Buy 29.8 oz HERE

Buy Ready-to-feed
Buy 20.1 oz HERE

Buy 30.2 oz HERE

Buy Ready-to-feed

Can you switch between Similac Pro Sensitive and Similac 360 Total Care Sensitive?

Yes, your baby can take Similac Pro Sensitive and Similac 360 Total Care Sensitive interchangeably because they are of the same type (lactose-reduced) and have the same purpose (help reduce fussiness and gas due to lactose sensitivity). Also, they have the same nutrient value.

The lack of some extra features doesn’t have a big impact on your baby’s health.

Final Thoughts:

The best alternative to Similac Pro Sensitive in the Similac brand is Similac Sensitive, Similac Total Comfort, Similac Pro Total Comfort, and Similac 360 Total Care Sensitive because they are of the same type (lactose-reduced formulas) and have the same nutrient value.

Image Credit:

Versus Vectors by Vecteezy

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