Similac Pro Advance Vs All Enfamil Formulas: Full Comparison

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Similac Pro Advance is a regular milk-based formula designed for babies who haven’t milk protein or lactose sensitivity. It’s made from nonfat milk, whey protein concentrate, and 100% lactose. Furthermore, it has an extra feature called OptiGro which is a blend of DHA, lutein, and vitamin E for eye, brain, and cell development.

Moreover, most babies like the taste of Similac Pro Advance, but it may cause gas for some.

In this article, we will see a full comparison between Similac Pro Advance and all Enfamil formulas. Stay with me!

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Similac Pro Advance vs Enfamil Infant:

Similac Pro Advance vs Enfamil Infant

Similac Pro Advance and Enfamil Infant are standard milk-based formulas designed for babies with no sensitivity issues made from nonfat milk, whey protein concentrate, and 100% lactose. The difference between them is that Enfamil Infant contains palm oil and has a whey-to-casein ratio of 60:40 whereas Pro Advance has 48:52.

Furthermore, Similac has introduced the OptiGro feature in the Pro Advance formula which is a blend of DHA, lutein, and vitamin E for eye, brain, and cell development, and it has the new HMO prebiotic (2′-FL HMO) to help promote the gut health.

In terms of nutrients and price, Enfamil Infant is enriched more than Pro Advance with vitamins and minerals and has a cheaper ready-to-feed form.

I did a full comparison between Enfamil Neuropro and Pro Advance if you want to check!

Mom’s Reviews Comparison:

Ingredients Comparison:

In terms of ingredients, Enfamil Infant and Pro Advance have the same protein and carbohydrate sources. However, they differ in whey-to-casein ratio and fat sources.

Similac Pro Advance doesn’t have palm oil among fat sources to ensure fat and calcium absorption by the baby’s body. Furthermore, it has a new feature called OptiGro which is a blend of Lutein, DHA, and Vitamin E to help promote eye health and brain development and to support cells development.

Moreover, Pro Advance has two prebiotics one of them (2′ FL) is an HMO prebiotic found in breast milk whereas Enfamil Infant has two regular prebiotics.

« HMOs are special prebiotics found naturally in a mother’s breast milk. They are the most abundant solid ingredient in breast milk after fat and carbohydrates. In breastfed babies, HMOs are scientifically shown to positively affect the microbiome. » says nutritionnews.Abbott

the average whey-to-casein ratio in breast milk is 70% to 30% and 80% to 20% in early lactation and 50% to 50% in late lactation.

Related: The best 9 generic brands of Similac Advance and Pro Advance

Nutrition Comparison:

In terms of Nutrition, Enfamil Infant is enriched with vitamins and minerals more than Similac Pro Advance. However, the inositol level in the latter formula is 4 times that in the regular Enfamil.

The average inositol level in breast milk during lactation is 22mg /100 Cal.

“Inositol is an essential nutrient required by human cells in culture for growth and survival. Inositol promotes maturation of several components of surfactant and may play a critical role in fetal and early neonatal life. A drop in inositol levels in infants with respiratory distress syndrome (RDS) can be a sign that their illness will be severe.”

Source: National Library of Medicine

Related: The Best 9 Generic brands of Enfamil Infant

Price Comparison:

Similac
Pro Advance
Enfamil Infant
30.8 oz
37.48 $
1.22 /oz

32-fl oz
10.42$
32.6 ¢/fl oz
12.5 oz
17.26 $
1.38 /oz

21.1 oz
25.27 $
1.20 /oz

29.4 oz
35.83 $
1.22 /oz

32 fl oz
8.98$
28.1 ¢/fl oz
4.5 of 5.0
665 reviews
4.8 of 5.0
3133 reviews
Buy 30.8 oz HERE

Buy Ready-to-feed
Buy 12.5 oz HERE

Buy 21.1 oz HERE

Buy 29.4 oz HERE

Buy Ready-to-use

Can you switch between Similac Pro Advance and Enfamil Infant?

Yes, you can switch between Similac Pro Advance and Enfamil Infant interchangeably because they are regular milk-based formulas and have the same protein, carbohydrate, and fat sources.

The absence of some ingredients (palm oil) or prebiotics doesn’t impact your baby’s health. The most important thing to consider is protein and carbohydrate sources.

Related: HiPP Combiotic VS Similac Advance & Pro Advance: Which One is The Best?

Similac Pro Advance vs Enfamil Enspire:

Similac Pro Advance vs Enfamil Enspire

Similac Pro Advance and Enfamil Enspire are both regular milk-based formulas made from nonfat milk, whey protein concentrate, and 100% lactose.

However, they differ in fat sources, Enfamil Enspire has palm oil, also, it’s enriched with vitamins and minerals more than Pro Advance whereas the latter is palm oil-free and has the new 2′-FL HMO prebiotic.

In terms of extra features, Enfamil Enspire has introduced Omega 3 DHA, MFGM (milk fat globule membrane) extracted from whey protein concentrate and protects against some infectious diseases and some cognitive benefits (brain development), and Lactoferrin which is a protein source that protects against viruses and infections and helps regulate iron absorption by the body.

In contrast, Pro Advance has the OptiGro feature which is a blend of DHA, lutein, and vitamin E for eye, brain, and cell development

Also read: 14 Easy Ways To Save Money On Baby Formula

Moms Reviews:

Nutrition Comparison:

Price Comparison:

Enfamil Enspire is more expensive than Pro Advance and doesn’t have a ready-to-feed form but it shows better results.

To know how much money you will save on Similac Pro Advance compared to Enspire, we must know how much formula a baby eats. Generally, a baby could eat up to 25 oz per day, which means almost 9000 oz per year.

If we do a quick math, Similac Pro Advance will cost up to 11000 $ whereas Enfamil Enspire will cost up to 17000 $, it’s 6000 $ of difference!!

Store brands will save you more money because they are cheap by half, also, they are safe and approved by the FDA.

Similac
Pro Advance
Enfamil Enspire
30.8 oz
37.48 $
1.22 /oz


32-fl oz
10.42$
32.6 ¢/fl oz
20.5 oz
39.98 $
1.95 /oz

30 oz
56.97 $
1.90 /oz
4.5 of 5.0
665 reviews
4.8 of 5.0
1693 reviews

Buy 30.8 oz HERE

Buy Ready-to-feed
Buy 20.5 oz HERE

Buy 30 oz HERE

Can you switch between Similac Pro Advance and Enfamil Enspire?

Yes, your baby can take Similac Pro Advance and Enfamil Enspire interchangeably in case you didn’t find your primary formula because they are of the same type (regular milk-based formulas) and have the same protein, carbohydrate, and fat sources.

The absence of some ingredients (palm oil), prebiotics, or extra features doesn’t impact your baby’s health. The most important thing to consider is protein and carbohydrate sources.

Similac Pro Advance vs Enfamil Reguline:

Similac Pro Advance vs Enfamil Reguline:

The difference between Similac Pro Advance and Enfamil Reguline is that the latter is a partially hydrolyzed and lactose-reduced formula by 50% designed to soften stools and helps with constipation thanks to the dual blend prebiotic (PDX and GOS) and low iron level (1.5 /100 Cal).

In contrast, Similac Pro Advance is a regular milk-based formula for babies with no health issues made from nonfat milk + whey protein concentrate and 100% lactose.

Mom’s reviews Comparison:

Ingredients Comparison:

Nutrition Comparison:

Price Comparison:

Similac
Pro Advance
Enfamil Reguline
30.8 oz
37.48 $
1.22 /oz

32-fl oz
10.42$
32.6 ¢/fl oz
12.4 oz
18.72 $
1.51 /oz

19.5 oz
29.98 $
1.54/oz
4.5 of 5.0
665 reviews
4.8 of 5.0
1020 reviews
Has RTF formNo RTF

Buy 30.8 oz HERE

Buy Ready-to-feed
Buy 12.4 oz HERE

Buy 19.5 oz HERE

Can you switch between Similac Pro Advance and Enfamil Reguline?

In case your baby has negative reactions to standard milk-based formulas due to intact cow’s milk protein or lactose, then you can switch to Enfamil Reguline because it has a gentle protein for your baby’s tummy.

However, if your baby is still sensitive to the intact cow’s milk, it’s not recommended to switch from Reguline to Pro Advance.

Final Thoughts:

Of all these formulas, the best alternative to Pro Advance in the Enfamil brand is Enfamil Infant, Enfamil Enspire, and Enfamil Neuropro because they are regular milk-based formulas made for babies with no health issues. In terms of price, Similac Pro Advance and Enfamil Infant are the cheapest in powder form whereas Enfamil Infant is the cheapest one in the ready-to-use form.

The other Enfamil formulas could be alternatives to Pro Advance in case your baby has an allergy to lactose or the intact cow’s milk protein.

Credit:

Versus Vectors by Vecteezy

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